The Japanese Association for Infectious Diseases

COVID-19 Publications from Japan:Clinical research

Last Update: January 12, 2021NEW
Successful Treatment with Methyl-prednisolone Pulses for the Late Phase of COVID-19 with Respiratory Failure: A Single-Center Case Series.NEW
Author name Tamura K, Nishioka S, Tamura N, Saito Z, Kuwano K.
Journal title 2020;31:101318. doi: 10.1016/j.rmcr.2020.101318.
The association of coagulopathy with liver dysfunction in patients with COVID-19.
Author name Tsutsumi T, Saito M, Nagai H, Yamamoto S, Ikeuchi K, Lim LA, et al.
Journal title Hepatol Res. 12 October 2020
Triple therapy with hydroxychloroquine, azithromycin, and ciclesonide for COVID-19 pneumonia.
Author name Mori N, Katayama M, Nukaga S.
Journal title J Microbiol Immunol Infect. 2020 Oct 5;S1684-1182(20)30237-1.  doi: 10.1016/j.jmii.2020.09.003. Online ahead of print.
Seroconversion against SARS-CoV-2 occurred after the recovery in patients with COVID-19.
Author name Yamamoto S, Saito M, Nagai E, Toriuchi K, Nagai H, Yotsuyanagi H, et al.
Journal title J Med Virol. 2020 Sep 8. doi: 10.1002/jmv.26495. Online ahead of print.
Antibody Response to SARS-CoV-2 in people living with HIV.
Author name Yamamoto S, Saito M, Nagai E, Toriuchi K, Nagai H, Yotsuyanagi H, et al.
Journal title J Microbiol Immunol Infect.
Clinical characteristics of 345 patients with coronavirus disease 2019 in Japan: a multicenter retrospective study.
Author name Ishii M, Terai H, Kabata H, Masaki K, Chubachi S, Tateno H, et al.
Journal title J Infect. 2020 Sep 10;S0163-4453(20)30590-9. doi:10.1016/j.jinf.2020.08.052. Online ahead of print.
Letter in response to article in journal of infection: “Clinical characteristics of 345 patients with coronavirus disease 2019 in Japan: A multicenter retrospective study”.
Author name Miyazawa D.
Journal title J Infect. 2020 2020 September 27; DOI:
Coronavirus Disease-19 Pneumonia with Facial Nerve Palsy and Olfactory Disturbance.
Author name Homma Y, Watanabe M, Inoue K, Moritaka T.
Journal title Intern Med. 2020;59(14):1773-1775. doi: 10.2169/internalmedicine.5014-20.
Management strategy of pregnant women during COVID-19 pandemic.
Author name Suzumori N, Goto S, Sugiura-Ogasawara M.
Journal title Aust N Z J Obstet Gynaecol. 2020 Aug;60(4): E9-E10. doi:10.1111/ajo.13202.
A Case of Coronavirus Disease 2019 Treated With Ciclesonide.
Author name Nakajima K, Ogawa F, Sakai K, Uchiyama M, Oyama Y, Kato H, et al.
Journal title Mayo Clin Proc. 2020 Jun;95(6):1296-1297. doi:10.1016/j.mayocp.2020.04.007
Protection of Dialysis Staff from COVID-19 Infection: Setting Up and Impact of Extended Blood Lines during Dialysis.
Author name Matsuoka R, Masuda T, Akiyama Y, Muto T, Miyamoto Y, Imai T, et al.
Journal title ASAIO J. 2020 Jul 16. doi:10.1097/MAT.0000000000001240.
Acute Onset Olfactory/Taste Disorders are Associated with a High ViralBurden in Mild or Asymptomatic SARS-CoV-2 Infections.
Author name Nakagawara K, Masaki K, Uwamino Y, Kabata H, Uchida S, Uno S, et al.
Journal title Int J Infect Dis. 2020 Jul 26;S1201-9712(20)30578-6. doi:10.1016/j.ijid.2020.07.034.
Significance of liver dysfunction associated with decreased hepatic CT attenuation values in Japanese patients with severe COVID-19.
Author name Uchida Y,Uemura H, Yamaba S, Hamada D, Tarumoto N, Maesaki S, et al.
Journal title J Gastroenterol. 2020 Aug 9. doi:10.1007/s00535-020-01717-4.
Humidifier Use and Prone Positioning in a Patient with Severe COVID-19 Pneumonia and Endotracheal Tube Impaction Due to Highly Viscous Sputum.
Author name Sugimoto R, Kenzaka T, Fujikawa M, Kawasaki S, Nishisaki H.
Journal title Cureus. 2020;12(6): e8626. Published 2020 Jun 15. doi:10.7759/cureus.8626
Acute Gouty Arthritis During Favipiravir Treatment for Coronavirus Disease 2019: A Case Report.
Author name Hase R, Kurata R, Ishida K, Kurita T, Muranaka E, Mito H.
Journal title Intern Med. 2020 Jul 28. doi:10.2169/internalmedicine.5377-20.
Therapeutic Potential of Ciclesonide Inahalation for COVID-19 Pneumonia: Report of Three Cases.
Author name Iwabuchi K, Yoshie K, Kurakami Y, Takahashi K, Kato Y, Morishima T.
Journal title J Infect Chemother. 2020 Jun;26(6):625-632. doi:10.1016/j.jiac.2020.04.007.
A case of imported COVID-19 diagnosed by PCR-positive lower respiratory specimen but with PCR-negative throat swabs.
Author name Hase R, Kurita T, Muranaka E, Sasazawa H, Mito H, Yano Y.
Journal title Infect Dis (Lond). 2020 Jun;52(6): 423-426. doi:10.1080/23744235.2020.1744711. ‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬
A case of non-severe COVID -19 complicated by pulmonary embolism.
Author name Akiyama Y, Horiuchi K, Kondo Y, Kabata H, Ishii M, Fukunaga K.
Journal title Respir Case Rep. ‭8‭(7),‭ ‬2020,‭ ‬e00622‬. doi:‬‬‬‬‬‬‬‬
Gargle Lavage as a Safe and Sensitive Alternative to Swab Samples to Diagnose COVID-19: A Case Report in Japan.
Author name Saito M, Adachi E, Yamayoshi S, Koga M, Iwatsuki-Horimoto K, Kawaoka Y, et al.
Journal title Clin Infect Dis. 2020 Apr 2; ciaa377. doi: 10.1093/cid/ciaa377.
Cases of Coronavirus disease-2019 in HIV-infected Transgender Women.
Author name Adachi E, Saito M, Ikeuchi K, Hoshina T, Yotsuyanagi H.
Journal title AIDS. 2020 Jul 15; 34(9):1435-6. doi:10.1097/QAD.0000000000002573.
Relative Bradycardia in Patients With Mild-to-Moderate Coronavirus Disease, Japan.
Author name Ikeuchi K, Saito M, Yamamoto S, Nagai H, Adachi E.
Journal title Emerg Infect Dis. 2020 Jul 1; 26(10). doi:10.3201/eid2610.202648.
Serum KL-6 can distinguish between different phenotypes of severe COVID-19.
Author name Nakamura H, Miyagi K, Otsuki M, Higure Y, Nishiyama N, Kinjo T, et al.
Journal title J Med Virol. 2020 Jul 7. doi: 10.1002/jmv.26268.
The peripheral lymphocyte count as a predictor of severe COVID-19 and the effect of treatment with ciclesonide.
Author name Yamasaki Y, Ooka S, Tsuchida T, Nakamura Y, Hagiwara Y, Naitou Y, et al.
Journal title Virus Res. 2020 Jul 3; 198089. doi:10.1016/j.virusres.2020.198089.
Statement on the prevention and treatment of COVID-19 in patients with pediatric cancer in Japan.
Author name Iehara T, Manabe A, Hosoi H.
Journal title Pediatr Blood Cancer. 2020 Jun 22; e28440. doi:10.1002/pbc.28440.
Natural history of asymptomatic SARS-CoV-2 infection.
Author name Sakurai A, Sasaki T, Kato S, Hayashi M, Tsuzuki S, Ishihara T, et al.
Journal title N Engl J Med. 2020 Jun 12; NEJMc2013020. doi: 10.1056/NEJMc2013020.
Continuous Renal Replacement Therapy for a Patient with Severe COVID-19.
Author name Katagiri D, Ishikane M, Ogawa T, Kinoshita N, Katano H, Suzuki T, et al.
Journal title Blood Purif. 2020 Jun 11; 1-3. doi:10.1159/000508062.
A case of SARS-CoV-2 infection in an untreated HIV patient in Tokyo, Japan.
Author name Nakamoto T, Kutsuna S, Yanagawa Y, Kanda K, Okuhama A, Akiyama Y, et al.
Journal title J Med Virol. 2020 Jun 3; 10.1002/jmv.26102. doi:10.1002/jmv.26102.
Treatment of two cases of COVID-19 with ciclesonide resulted in amelioration of pneumonia symptoms.
Author name Tsuchida T, Yamasaki Y, Kunishima H, Sato K, Kanazawa M, Moriuchi A, et al.
Journal title Jpn J Antibiot. 2020 Jun; 73(2): 35-44.
Pharmacokinetics of Favipiravir in Critically Ill Patients With COVID-19.
Author name Irie K, Nakagawa A, Fujita H, Ryo Tamura R, Eto M, Ikesue H, et al.
Journal title Clin Transl Sci. 2020 May 31; 10.1111/cts.12827. doi:10.1111/cts.12827.
Clinical course of 2019 novel coronavirus disease (COVID-19) in individuals present during the outbreak on the Diamond Princess cruise ship.
Author name Kato H, Shimizu H, ShibueY, Hosoda T, Iwabuchi K, et al.
Journal title J Infect Chemother. May 13; 26(8):865-869. doi:10.1016/j.jiac.2020.05.005.
Psychiatric burdens or stress during hospitalization and concerns after discharge in patients with severe acute respiratory syndrome coronavirus-2 isolated in a tertiary care hospital.
Author name Morioka S, Saito S, Hayakawa K, Takasaki J, Suzuki T, Ide S, et al.
Journal title Psychiatry Res. 2020 Apr 29; 289:113040. doi:10.1016/j.psychres.2020.113040.
Nursing care for patients with COVID-19 on extracorporeal membrane oxygenation (ECMO) support.
Author name Umeda A, Sugiki Y.
Journal title Glob Health Med. 2020 Apr; 2(2):127-30. doi:10.35772/ghm.2020.01018
Clinical course of a critically ill patient with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Author name Takahashi N, Abe R, Hattori N, Matsumura Y, Oshima T, Taniguchi T, et al.
Journal title J Artif Organs. 2020 Jun 16;1-4. doi:10.1007/s10047-020-01183-y.
Imported and Locally Transmitted Mild SARS-CoV-2 Pneumonia Cases in Japan.
Author name Tochitani K, Iwamoto N, Motobayashi H, Yamamoto S, Tsunehiro Shimizu.
Journal title J Infect Chemother. 2020 Aug; 26(8):854-857. doi:10.1016/j.jiac.2020.05.014.
Clinical characteristics of the coronavirus disease 2019 (COVID-19) outbreak on a cruise ship.
Author name Yoshimura Y, Sasaki H, Horiuchi H, Miyata N, Tachikawa N.
Journal title J Infect Chemother. 2020 Jun 12; S1341-321X(20)30196-3. doi:10.1016/j.jiac.2020.06.010.
Prolonged presence of SARS-CoV-2 in a COVID-19 case with rheumatoid arthritis taking iguratimod treated with ciclesonide.
Author name Baba H, Kanamori H, Oshima K, Seike I, Niitsuma-Sugaya I, Takei K, et al.
Journal title J Infect Chemother. 2020 July 1;

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